How to Properly Brush your Teeth

By nano-b

Simply brushing your teeth is not enough. Include these PROPER techniques in your habit. The Oral Surgery DC

It seems incredible how universal the habit of teeth brushing is all over the world. It might very well be the most widely practiced health habit people do on a daily basis. This fact left us to wonder why are we brushing our teeth?

Is it because we were told to do so when we were kids and the habit got integrated very firmly in our daily routine? Is it because we are dreading the dentist so much and think brushing is the best way to prevent meeting him? Whatever the reason is, it is great that billions of people brush their teeth every day, as the health of our gums and teeth is very closely connected to the wellbeing of the whole body.

The fact that we brush our teeth every day is great and really important, but it’s even more important that we do it properly. Brushing your teeth the proper way can make a huge difference and can improve your oral health significantly. So, let’s dive into the basics.

Choosing The Right Toothbrush

Not all toothbrushes are created equal. It’s soothing to think of all toothbrushes as our allies that help us be healthier. Unfortunately, there are still a lot of cheap products with inferior quality on the market and many people underestimate the importance of using a safe, high-quality toothbrush. Both manual and powered toothbrushes are linked to damaging our teeth and gums and it is of crucial importance to use safe dental products.

Having the wrong brush can damage our teeth and gums and cause sensitivity and sometimes even more serious problems. That’s why we have to be smart when choosing a toothbrush and know what we need from one. A safe toothbrush should have:

  • Rounded bristles –  so it protects your enamel and the soft tissue of your gums from scratches.
  • Small head size – you should be able to reach and clean effectively all of your teeth.
  • Bristles should not be frayed – frayed bristles cannot remove plaque effectively and are a clear sign that you should replace your toothbrush.
  • Comfortable in our hand and mouths – you shouldn’t feel any discomfort while you brush
  • Antibacterial – Bacteria from your toothbrush can enter your bloodstream, so make sure your toothbrush is clean and safe.

The other most widely used product in our daily oral hygiene routine is the toothpaste. Up until recently, people rarely paid attention to what toothpaste they were using. Fresh taste, recognizable brand and a decent price were all the factors users have considered. However, as customers become more and more educated other important factors start to weight more in the buying decision. This has sparked a new debate about what type of toothpaste should we use. Should it be organic or not? Should it contain fluoride? Should it be tested on animals Should it be with all natural ingredients?

There are as many opinions as there are toothpaste brands on the market, but we strongly believe that the products we use in our daily life should reflect our values and understanding of what the world should be like. Hence, we strongly recommend toothpaste products that are all natural and preferably with organic ingredients. Products that don’t contain any artificial and potentially harmful chemicals, allergens, etc. And of course, products that have not been tested on animals.

At Nano-b, we truly believe that the products we use reflect who we are. Choosing the right toothbrush and toothpaste might seem like a trivial decision, but for us, it’s a reflection of our values and our desire to live a healthier life while remaining close to nature.

Time and consistency is KEY

We should brush at least 2 times per day for at least 2 minutes. Every day!

For every health habit, you want to build and maintain consistency is key. Dental problems can indeed be avoided with proper and consistent oral care routine. It is very important to brush your teeth every day for at least two minutes and never skip a brushing. you don’t want to leave plaque and bacteria in your mouth for a long time as tooth erosion and inflammation processes can start quickly.

Timing is really important as well. If it feels like you are rushing and not brushing for long enough, setting a timer might be a good idea. Or you can just play your favorite song and brush while it plays!

If you brush twice a day for two minutes the time spent brushing sums up to just about 24 hours per year that we invest in our health. Just one day per year and we can be healthier, happier and avoid the dreaded dental procedures.

Of course, a proper toothpaste and toothbrush are crucial and consistency will always be a very important component, but it’s equally important that you use the right brushing technique, otherwise all our efforts might be in vain. You would guess that all that brushing has turned us into experts, but unfortunately, most people don’t brush properly, which not only will diminish the health benefits of brushing but might even pose some dangers to your teeth and gums.

The Right Technique

You’ve probably heard the advice “Place your toothbrush at a 45 degrees angle”. It sounds very scientific and credible, but what it really means is that you have to aim for where the gums and teeth meet and food particles stack up. The angle also allows for a more gentle approach, that is not only more effective for cleaning but it also doesn’t damage your teeth and gums.

Use gentle, circular, massaging motion. IT’s VERY IMPORTANT that you don’t apply a lot of pressure to your teeth. In reality, the more gentle you brush, the better the results. Don’t squeeze your toothbrush, hold it very gently and apply a very slight pressure to your teeth and gums. Let the toothbrush bristles do their job, you don’t need to press too hard at all.

If you are to remember only one thing from this post, it should be to use circular, massaging motions. Gentle, circular motions will allow toothbrush bristles to get between your teeth and under the gumline and clean as much plaque as possible. Fast and hard movements will do the opposite and the bristles won’t be able to clean where the most plaque is formed.

Make sure you don’t miss any spots and clean all sections of your mouth (top, bottom, left, and right). All of your teeth are equally important and deserve the same attention. Dedicate the same time to each section of your mouth to make sure no teeth are neglected. Make sure the head of your toothbrush is small and nimble enough, so it can easily reach and clean the hard-to-reach places in your mouth (like your back teeth).

Hold your brush vertically to clean the back side of your front teeth with up and down strokes. This is a part of the mouth that is often neglected and not cleaned properly. You should pay special attention to your bottom front teeth as this is the place where many problems might develop if not cleaned properly and consistently.

Start from a different place every time, so you don’t develop a habit of missing or spending less time on the same spots.

Try brushing with your other hand from time to time.This is a really cool life hack that will not only keep you more focused during brushing but will also make you smarter! Many studies suggest that using your non-dominant hand for trivial tasks from time to time improves your brain functions. It turns out brushing your teeth will not only keep you healthy but make you smarter as well!

It’s also a good idea to even try brushing with your eyes closed, so you can concentrate more on proper technique. It will help you focus more and avoid getting bored from brushing the same way every day.

Brush your tongue. It’s where most of the bacteria in your mouth are harbored. It’s best to do it with a tongue scraper, designed for that. A toothbrush will never be effective enough – it has another purpose.


What NOT to do

Don’t scrub/press too hard. Teeth aren’t something you should scrub. Plaque is soft and loose. WebMD advises us to replace the word “scrub” with “massage” when we think about the proper brushing technique. This will help us have a better mental image of the proper way to brush.

Don’t rush or spending too much time brushing. As mentioned above, both of those mistakes can lead to some teeth and gum problems. If you are rushing and using too fast movements, you are not allowing the bristles to properly get between your teeth and remove plaque effectively. On the contrary, if you are spending too much time and brushing too vigorously on the same spot, you might be wearing your enamel or irritating your gums.

Going back and forth, side to side is a nightmare for your teeth. You are jeopardizing your enamel and gums, while not removing plaque efficiently. Remember the proper way is to use gentle, circular motions.

Don’t forget your gums. Your gum line is where the biggest dangers to your oral health lie. You should pay close attention and brush gently where your teeth and gums meet. Neglecting this area might lead to unpleasant gum diseases.


Brushing in the morning

It’s strongly recommended that you brush your teeth first thing in the morning. But why should we even brush in the morning, if we did it just before going to bed and didn’t consume any foods or drinks (except water) overnight?

It’s a good idea to clean out the existing bacteria in your mouth that have been developing overnight. Otherwise, you will be ingesting all that bacteria together with your breakfast. Your mouth is drier in the morning because saliva levels are lower while you sleep, hence, it’s easier for bacteria to develop in such environment.

Brushing before breakfast increases your saliva levels and thus, protects your teeth from any acidic or potentially erosive foods that you are about to consume. In addition, you’d want to avoid brushing right after breakfast (wait at least 15-20 minutes), because if you consume any acidic foods or drinks (coffee and orange juice count as well), your teeth are susceptible to a greater acidic damage and erosion and sensitive teeth.

Since you don’t want to brush your teeth immediately after breakfast, it’s a good idea to remove any sugars by rinsing your mouth with water several times.

Brushing in the evening

Ideally, it’s best to brush your teeth after every meal. However, we realize this is not always possible, so if you are brushing your teeth twice a day, the best time (in addition to the morning brushing), is in the evening after your last meal. It’s recommended to brush at least 20 minutes after a meal, because of the same acids, mentioned above.

Going to bed without brushing your teeth can be extremely dangerous for your teeth, as all the bacteria in your mouth can feed on all of the food you’ve had throughout the day and produce acids that break down tooth enamel and cause cavities. In addition, the lower saliva level during the night is very beneficial for the bacteria as saliva is the best natural defense against the acids produced by the bacteria in your mouth.


A few extra things that are good to know about brushing

  • Toothbrushes should be replaced after their bristles start to fray. They are not as effective in removing plaque and can even cause minor damages to your teeth and gums. Normally, most toothbrushes start to fray after 2-3 months, depending on your brushing style. Nano-b toothbrushes last up to 6 months and don’t fray nearly as much.
  • After you go through the flu, you should replace your toothbrush. The bacteria stays on the toothbrush and you risk to catch the same virus again. Of course, you don’t have to replace your brush if you are using Nano-b, as we’ve made our brushes antibacterial to protect your health from threats like this.


You spend a day of each year brushing your teeth and it really makes a difference if you do it properly. It’s the most widely practiced health habit around the world and for a good reason, as it is a really vital component of our overall health and wellbeing. Hopefully, you now know all the basics and will pay more attention each time you brush.

Stay healthy and happy brushing!

The Nano-b Team

Your teens may think that they don’t need you anymore, but they’ll always need their teeth!

By Campaign for Dental Health

 👦👧Your teens may think that they don’t need you anymore, but they’ll always need their teeth!

They will thank you for setting the foundation for good oral health by modeling the best practices and having them see a dentist regularly. Read more here: and if you need help finding a dentist for your teen visit: The Oral Surgery DC Team

Do you remember chasing your toddler around trying to brush his teeth before bed? You may not have to do that anymore, but oral health is as important for adolescents as it was when they were little, maybe even more so. During adolescence, we want to be sure that children continue effective oral hygiene habits such as brushing twice a day with fluoride toothpaste, flossing, seeing a dentist, eating a healthy diet that is low in sugar, and drinking water with fluoride.

Adolescents also have other things to consider when it comes to their oral health such as using tobacco or marijuana productsdealing with braces, using mouth guards while playing sports, and all of the changes that are happening with their bodies. They will continue to need your guidance in making decisions that affect their overall health and oral health, but it is also time for them to take the wheel to make sure they have teeth for life. Good oral health is important for getting a job and a girlfriend/boyfriend – you can decide which message works better for your teen!

They will thank you for setting the foundation for good oral health by modeling best practices, having your child see a dentist regularly, and making sure he had all of the needed preventive treatments, such as sealants, fluoride applications, orthodontics, and fillings, when needed. If you need help finding a dentist for your teen visit

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New Implant Advancement Hopes to Lower Risk of Infection

By: KU Leuven, Oral Health Group

😀 New research has developed a dental implant that can gradually release drugs from a built-in reservoir which helps prevent and fight infections:

Visit our website to learn more about dental implants: The Oral Surgery DC Team

A multidisciplinary team of researchers at KU Leuven (University of Leuven, Belgium) has developed a dental implant that gradually releases drugs from a built-in reservoir. This helps prevent and fight infections.

Our mouth contains many micro-organisms, including bacterial and fungal pathogens. On traditional dental implants, these pathogens can quickly form a so-called biofilm, which is resistant to antimicrobial drugs like antibiotics. As a result, these implants come with a significant risk of infections that may be difficult to treat.

KU Leuven researchers have now developed a new dental implant that reduces the risk of infections. “Our implant has a built-in reservoir underneath the crown of the tooth,” explains lead author Kaat De Cremer. “A cover screw makes it easy to fill this reservoir with antimicrobial drugs (see image 1). The implant is made of a porous composite material so that the drugs gradually diffuse from the reservoir to the outside of the implant, which is in direct contact with the bone cells (see image 2). As a result, the bacteria can no longer form a biofilm.”

To view the full story, please click here.

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Can You Get Through This Post Without Wanting To Brush Your Teeth?

By: Kelly Oakes, BuzzFeed

😏 CHALLENGE: Try getting through this disturbing article without wanting to brush your teeth! The Oral Surgery DC Team

Here’s what your teeth look like up close and personal with a scanning electron microscope.

This is a calcium phosphate crystal, the stuff that makes up your tooth enamel.

Here’s some plaque forming bacteria, magnified 1000 times. It really likes to hang out on your teeth.

See: here’s the surface of a human tooth. Bacteria is coloured blue, red blood cells are red.

When you let the bacteria stick around, plaque starts to form.

Brushing can keep the plaque at bay. This is a single bristle from a used toothbrush.

And another.

Here’s the bristles of an interdental brush covered in plaque.

Some more of that lovely plaque-forming bacteria that forms on your teeth. Super cute and cuddly!

It just wants to be your friend.

 It just wants to be your friend.

Look away now if you’re squeamish. This is a tooth with a cavity.

And don’t forget about your gums. These are the bacteria that live in them.

Brb brushing my teeth.

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New material used in molar extraction sites optimizes bone regeneration and dental implant stability

By: Journal of Oral Implantology

🤓 [Good to know]: New material used in molar extraction sites optimizes bone regeneration & dental implant stability. Curious to learn more? The Oral Surgery DC Team

Journal of Oral Implantology – Dental surgery is a difficult, painful process no matter what the procedure, but having a tooth extracted and an implant put in months later can result in major complications. The longer you wait for the implant, the greater the likelihood that formation of scar tissue or shifting of teeth will occur to compensate for the loss of the extracted tooth; this can cause problems when it is time to insert the new implant.

Great advancements in dental surgery have been made to assist with bone and tissue regeneration so that when it is time to insert the implant, the extraction site has been stabilized and a graft performed to protect the integrity of the site. The article “Guided Bone Regeneration for Socket Preservation in Molar Extraction Sites: Histomorphometric and 3D Computerized Tomography Analysis” in the Journal of Oral Implantology introduces a new, more advanced method for this regeneration that prevents infection and maximizes bone regeneration.

The most commonly used treatment for post-extraction regeneration has been a combination of acellular dermis matrix (ADM), a type of bone regenerating material that uses cadaveric tissue with all of the cells removed, and different grafting procedures. However, there has been no solid histologic data or microscopic tissue samples to prove that this regeneration is working properly.

This case series examines a new ADM replacement material called decellularized dermis matrix (DDM) that, combined with mineralized bone grafts called mineralized cancellous bone allograft (MCAB), guides the regeneration of bone to allow for a more stable placement of the implant. This method has a higher regeneration percentage and supports a more stable future implant site than previous therapies.

Tissue samples were examined both microscopically and using 3D imaging. Valuable surgery preparation time was saved using DDM, which can be stored fully hydrated, and the material was easy to handle and adapted well to the shape of extraction-site defects. A minimum of 12 weeks post extraction, the study found that none of the molar extractions had developed infections. A loss of bone volume was also prevented, allowing for optimal implant placement and stability. These results demonstrate the value of DDM and MCAB in preparing molar extraction sites to support implant placement.

Full text of the article, “Guided Bone Regeneration for Socket Preservation in Molar Extraction Sites: Histomorphometric and 3D Computerized Tomography Analysis,” Journal of Oral Implantology, Vol. 39, No. 4, 2013, is available here.

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By: Listerine

🐮 Beyond just limiting the sugary sweets and harsh acidic foods in your diet, incorporate foods that are good for your gums, too! The Oral Surgery DC Team

Routine brushing, flossing, and rinsing keep your mouth in good health. And while you need these powerful weapons in your bacteria-fighting arsenal, you could always use reinforcement. Beyond limiting the sugary sweets and harsh acidic foods in your diet, there are foods that are good for your gums.

A Better Way to Add Flavor

Ginger root is considered a healing herb. With its anti-inflammatory properties, ginger promotes healthy tissue in your mouth.

Keep More Than the Doctor Away

Eating an apple can take a while. And that’s a good thing for your mouth. The munching action spurs a cleansing action that shakes up the plaque that clings to gums and teeth. Stock up on apples, but be sure to rinse with mouthwash afterward. Even healthy foods like apples can expose your mouth to acids.

Got Milk in Your Diet?

Milk and other dairy foods such as cheese and yogurt are not only packed with bone-fortifying calcium, but also with the protein casein, which research suggests reduce acid levels in the mouth. In addition, drinking milk can neutralize acids produced by plaque bacteria. Note: Drinking milk with cereal or dessert doesn’t have the same benefit as direct consumption after eating. No milk around? Eat a piece of cheese instead.

Load Up on Leafy Greens

It’s no secret that salad greens pack an all-around healthy punch, but they’re also especially successful at keeping mouths clean because they’re fiber-packed, meaning they require serious chewing to break down. The extra saliva produced by chewing neutralizes mouth bacteria. High-fiber, stringy foods like raw spinach, celery, and even cooked beans offer this benefit.

Zap Bacteria, Layer by Layer

The raw onion is a potent bacteria-fighting food. Yes, bad breath is the enemy. But that’s why sugarless gum and mouthwash were created. Onions have an antimicrobial ingredient that kills bacteria, and, according to one study, completely wipes out four bacteria strains that lead to gum disease and cavities. Sliver them and toss the strips in your salad, on your sandwich and burger or in soups and stews.

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A Year of Oral Health Guidance in Review

By David Cavano, Dental Health

Summer is here! Here’s some oral health guidance from the past year to help you understand what new information is available and which tried-and-true practices still stand. The Oral Surgery DC Team

Sometimes it is hard to keep up with all of the new guidance about our health. What we were told yesterday is healthy, is now unhealthy today. Here, I have distilled down some of the oral health guidance from the past year so you can understand what new information is available and which tried-and-true practices still stand.

Toss Teething Tablets

The Food and Drug Administration (FDA) has warned against the use of homeopathic teething tabs and drops that contain belladonna. An FDA Press Release instructed consumers not to use Hyland’s teething products and to dispose of any in their possession. Hyland’s Teething Tablets are manufactured to contain a small amount of belladonna, a substance that can cause serious harm at larger doses. FDA laboratory analysis has discovered that Hyland’s Teething Tablets contain inconsistent amounts of belladonna.

Safe teething relief strategies to try: Gently massage areas near erupting teeth using a clean finger. Cool objects may provide relief, so consider chilled (not frozen) washcloths, a semi-frozen banana or a commercial teething ring. Make certain teething rings are of one-piece construction, free of painted surfaces, and sufficiently large to avoid choking.

Weigh the Risks and Benefits of General Anesthesia and Sedation Drug Use in Children

In January 2017, the American Academy of Pediatrics (AAP) responded to the  FDA warning on general anesthesia and sedation drug use in children. This warning includes the possibility of developmental problems associated with the repeated or prolonged use of anesthetics in children younger than 3 years of age. The FDA advisory committee has been reporting about the concerns regarding anesthesia in young children since 2007 and aims to increase awareness in providers enabling the provision of education for families and subsequently informed consent.

Section and AAP Leadership worked together, along with several other societies, to form a response to this warning. These groups have reviewed recent controlled trials in humans as well as multiple epidemiological studies of large populations that demonstrate no developmental problems in children exposed to a single, short anesthetic or sedation. The response cautions parents and providers of the risks of delaying needed surgery and diagnostic procedures and suggests weighing the risks and benefits of each contemplated procedure.

Use Fluoride Toothpaste in Young Children

The AAP, American Academy of Pediatric Dentistry (AAPD), and the American Dental Association (ADA) all agree that fluoride toothpaste should be used for all children, regardless of age. Upon arrival of the first primary tooth, parents should begin using a grain-of-rice sized amount of fluoridated toothpaste regardless of both water fluoride content and cavities risk status. Brushing is advised twice daily, ideally after a morning meal and always prior to bedtime.

Use Toothpaste to Deliver Fluoride, Not to Remove Plaque

December 2016 Journal of Clinical Periodontology. Toothpaste does not provide an added effect for the mechanical removal of dental plaque. However, toothpaste use should continue as it promotes oral health as a delivery system for fluoride and antimicrobials.

All Children Should Receive Fluoride Varnish Application

All children, regardless of risk may receive fluoride varnish applications in the primary care setting. The frequency of application is dependent upon the compliance with the use of a dental home as well as cavities-risk.

Recent studies published in the September 2016 Journal of the American Academy of Pediatric Dentistry continue to demonstrate the safety of fluoride varnish, concluding that biannual fluoride varnish application in preschoolers is not associated with the occurrence of any level of fluorosis in permanent maxillary incisors.

Drink Water with Fluoride

In 2017, community water fluoridation programs continue to be the most effective and affordable way to prevent dental caries in children and adults. Although there were no new recommendations this year, we must all continue to advocate for this practice and recommend that our patients and their families drink water with fluoride for cavity-protection.

While the above is not a comprehensive listing of all professional guidance around oral health, they may well be the most important messages to share during National Children’s Dental Health Month and throughout the year.

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Consider the Evidence: Fluoride For Healthy Futures

By: Mirissa D. Price, Huffington Contributor

[OPINION]: Fluoride represents a major step toward not just treatment, but also prevention in oral health. Fluoride for healthy futures! The Oral Surgery DC Team

On February 1, 2016, in the late hours of the night, my jaw fell to the floor. I just couldn’t believe what I was seeing: is an independent news resource that covers the natural health and wellness topics that empower individuals to make positive changes in their personal…



And I truly hoped that none of the viewers would believe what they were seeing, either. Because it wasn’t based on evidence – not the kind prefaced by the word ‘science.’

And though a year has gone by since this Dr. Oz episode aired, I just couldn’t let the date pass without a call to action. To all readers, to all viewers, to you Ms. Brockovich, and you Dr. Oz, I don’t ask that you change your mind. Not necessarily. But I do ask that you read this statement drafted with a number of my HSDM 2019 DMD Candidate colleagues, and consider the evidence – the scientific evidence. Because, as a 2019 DMD Candidate at Harvard School of Dental Medicine and a future pediatric dentist, I care about your health today and in the future; I care about our communities’ health, and the health of our children, and I care that we make the right choices for everyone today. So, for just a moment, consider . . .

Harvard School of Dental Medicine practices dentistry under a philosophy of evidence-based medicine, providing patients with an up-to-date and research-based quality of care. Unfortunately, the antifluoridation segment on the Dr. Oz show on February 1, 2016, left much to be wanted regarding evidence-based care. In a one-sided depiction of Erin Brockovich’s anti-fluoridation rhetoric, this episode gravely misrepresented the strong foundation of research in support of community water fluoridation. In doing so, this episode not only threatened a public health measure supported by over one hundred health organizations, including the American Association of Public Health Dentistry and American Dental Association, but threatened the oral health and wellbeing of the most vulnerable communities in our nation.

Community water fluoridation took root in Grand Rapids, Michigan, in 1945. Soon, with a capacity to flow beyond the barriers to care dividing our society, community water fluoridation flourished as one of the greatest public health achievements of the twentieth century. Though only 37% of adults will actually visit a dentist in a given year, as of 2012, 200 million people in the United States received service from fluoridated water systems. These 200 million individuals thus had access to not only the remineralizing benefits of fluoride at the tooth surface and corresponding reduction in dental caries, but the associated increase in life satisfaction, employment success, and social confidence.

Unfortunately, Erin Brockovich, an environmental activist, misrepresented the impact of fluoride. She alluded to health risks of fluoride toxicity, citing the decreasing fluoride concentration in water from 1.2 to 0.7 mg/L as evidence of her claims. She further instilled fear in products vital to sustained oral health, including fluoridated toothpaste and natural foods. However, Ms. Brockovich failed to mention that the established safe fluoride levels are less than one-half the Maximum Concentration Limit, and all created within standards of the American Water Works Association and NSF International. Further, she fell short in factually supporting her claims of grandeur, misrepresenting the prevalence of dental fluorosis when this condition, in severe state, only presents in fewer than 1% of the population. The evidence in favor of fluoride is of such strength that even pediatricians are seeking to provide topical fluoride application in the pediatric medical home.

Fluoride represents a major step towards not just treatment but prevention in oral health. The use of fluoridated toothpaste and community water fluoridation has reduced the prevalence of dental caries from 90 to 30% among those age 12-17 years since the 1960s. Caries in adults have also seen significant decline since the introduction of community water fluoridation from 18 affected teeth on average among 35-44 year old adults in the 1960s to 10 affected teeth on average among 35-49 year olds in 1999-2004. As Americans are living longer, so, too, must our teeth, and scientific evidence overwhelmingly concurs that community water fluoridation is a vital component to sustaining our oral health and quality of life.

Thus, with respect for all voices and concern, the dental-medical community asks that the Dr. Oz Show and its viewers consider the scientific evidence in support of community water fluoridation as a strong and guiding voice of its own. Our choices today regarding community water fluoridation most certainly will affect the oral health and quality of life for our children tomorrow.

This statement was drafted as a collaboration of 2019 DMD Candidates at Harvard School of Dental Medicine as part of the Global and Public Health Curriculum, and does not represent an official response statement of HSDM.

Specific contribution is attributed to Jacquelyn Chou, 2019 DMD Candidate Harvard School of Dental Medicine; Justin Montenegro, 2019 DMD Candidate, Harvard School of Dental Medicine; Deepti Shroff, 2019 DMD Candidate, Harvard School of Dental Medicine; Edirin Sido, 2019 DMD Candidate, Harvard School of Dental Medicine; Mirissa D. Price, 2019 DMD Candidate, Harvard School of Dental Medicine; and additional 2019 DMD Candidates at Harvard School of Dental Medicine.


The doctor said she would live in a nursing home, confined to a wheelchair, crippled by pain; that was thirteen years ago. Instead, Mirissa D. Price is a 2019 DMD candidate at Harvard School of Dental Medicine, spreading pain-free smiles, writing through her nights, and, once again, walking through her days.

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End of fillings in sight as scientists find Alzheimer’s drug makes teeth grow back

The days of fillings could be over after scientists find a drug stimulates stem cells in teeth


By Sarah Knapton, Telegraph❗️ Fillings could be sent to the history books after scientists discovered that a drug, already in trials for Alzheimer’s patients, can encourage tooth regrowth and repair cavities! The Oral Surgery DC Team

Fillings could be consigned to history after scientists discovered that a drug already trialed in Alzheimer’s patients can encourage tooth regrowth and repair cavities.

Researchers at King’s College London found that the drug Tideglusib stimulates the stem cells contained in the pulp of teeth so that they generate new dentine – the mineralized material under the enamel.

Teeth already have the capability of regenerating dentine if the pulp inside the tooth becomes exposed through a trauma or infection, but can only naturally make a very thin layer, and not enough to fill the deep cavities caused by tooth decay.

An image showing repair after four weeks (left) and six weeks (right)

But Tideglusib switches off an enzyme called GSK-3 which prevents dentine from carrying on forming.

Scientists showed it is possible to soak a small biodegradable sponge with the drug and insert it into a cavity, where it triggers the growth of dentine and repairs the damage within six weeks.

The tiny sponges are made out of collagen so they melt away over time, leaving only the repaired tooth.

Professor Paul Sharpe, lead author of the study, of the Dental Institute, from King’s College London, said: “The simplicity of our approach makes it ideal as a clinical dental product for the natural treatment of large cavities, by providing both pulp protection and restoring dentine.

“In addition, using a drug that has already been tested in clinical trials for Alzheimer’s disease provides a real opportunity to get this dental treatment quickly into clinics.”

Currently, dentists use man-made cements or fillings, such as calcium and silicon-based products, to treat larger cavities and fill holes in teeth.

But this cement remains in the tooth and fails to disintegrate, meaning that the normal mineral level of the tooth is never completely restored.

However, the new technique could reduce the need for fillings of cements, which are prone to infection and often need replacing a number of times.

When fillings fail or infection occurs, dentists have to remove and fill an area that is larger than what is affected, and after multiple treatments the tooth may eventually need to be extracted.

Dr Nigel Carter, CEO of the Oral Health Foundation: “This is an extremely interesting and novel approach which shows great promise and we will look forward to it being translated into clinical application that could undoubtedly be a progressive step in the treatment of dental disease.

“While fillings have remained highly effective in repairing large cavities, they are susceptible to wear-and-tear and can occasionally be in need of repair and replacement. This presents problems as the dentist could have to remove and fill a larger area each time and after numerous treatments the tooth may then have to be extracted.

“Creating a more natural way for the tooth to repair itself could not only eliminate these issues, but also be a far less invasive treatment option for patients. With dental phobia still being very common, using a natural way to stimulate the renewal of dentine could be an especially comforting proposal for these groups, for which undergoing treatment can often be a cause great anxiety.”

The procedure has so far only been used in mouse teeth, but it was shown to ‘fill the whole injury site’.

And Tideglusib has already been shown to be safe in clinical trials of patients with Alzheimer’s disease so scientists say that the treatment could be fast-tracked into dental practices.

The research was published in the journal Scientific Reports.

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By Dental Asia

🎉 Good news!! The latest technology will make dental implants easier for patients and surgeons, which means no incisions, minimal discomfort and little disruption! The Oral Surgery DC Team

Dental implants have come a long way. New technology makes it possible to place these tooth root substitutes with no incisions, minimal discomfort, and little disruption to the patient’s life. The latest in dental implant coatings, nanostructured titanium, is even stronger and heals even faster than implants using conventional coatings.

An article in the current issue of the Journal of Oral Implantology reports on the use of this nanostructured titanium and techniques that can shorten the treatment time for a patient. These implants should also decrease the risk of implant failure and disease complications.

When patients need a dental implant, they naturally want their new tooth quickly and with as little pain as possible. Both can be achieved with the latest advances in implant technology. Guided surgery allows an implant to be placed quickly without incisions, and new implant materials let the surgeon set a crown on the implant straight away.

This case report used the latest technology to even greater effect. In this case, the patient needed an implant to replace a missing front tooth. The surgeon successfully combined model-guided surgery with immediate placement of a nanostructured titanium implant, a final abutment, and the tooth.

The nanostructured titanium integrates with the bone faster, is stronger, and is less susceptible to disease than conventional implant materials. The model-guided surgery is highly accurate yet less expensive than computer-based techniques. By using a thin acupuncture needle, the surgeon was able to create the model without anesthetizing the patient. By keeping the original root structure, the surgeon was able to lessen the risk of gum recession.

The combination resulted in a successful implant, without the receding gums often visible when an implant patient smiles. The flapless surgery involved less pain compared to incision-based techniques. The faster process reduced disruption in the patient’s eating and other daily living habits, and discomfort was minimal.

The author concluded that these types of implants have great promise and that nanostructured titanium is particularly appropriate for immediate placement of the implant and tooth. The author noted: “The patient was pleased with the aesthetic result, the improvement in function, and the ease of maintenance.”

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